Ultherapy PRIME ® is a non-invasive cosmetic procedure that uses time-tested ultrasound technology to stimulate the formation of new collagen deep below the skin’s surface. The procedure takes about 30 to 90 minutes, depending on the area treated, and there is no downtime afterward. It also is the only procedure to use ultrasound imaging, which allows practitioners to actually see the layers of the tissue targeted during the treatment and ensure the energy is deposited precisely to where it will be most beneficial.